Grapefruit juice interaction with drugs can be deadly - Health. More prescription drugs are on the market that can interact with grapefruit juice with potentially serious effects including sudden death, Canadian doctors warn. David Bailey, a clinical pharmacologist at the Lawson Health Research Institute in London, Ont., discovered the interaction between grapefruit and certain medications more than 2. Since then, he said, the number of drugs with the potential to interact has jumped to more than 8. Grapefruit juice is known to interact with some types of medications, leading to an overdose hazard. Bailey reviews new product monographs and prescribing information for the Canadian Pharmacists Association, and keeps a close eye on those with the potential to produce serious adverse reactions. Others include agents used to fight cancer or suppress the immune system in people who have received an organ transplant. People older than 4. Monday's issue of the Canadian Medical Association Journal, titled . So it's not surprising that these levels go from what we call therapeutic to toxic. They also suggested noninteracting alternatives that could be prescribed. But the authors can't say how big a problem the interactions are because of a lack of awareness. Health- care professionals might not be aware of the possibility to check into it and patients may not volunteer the information, Bailey said. David Bailey originally tested for an interaction between grapefruit juice and a medication in himself. June 3. 0, 2. 01. The department cautioned that the data was voluntarily reported and should not be used to determine the incidence because the total number of reactions and patients exposed is unknown and other factors could be contributing. Selected drugs that interact with grapefruit. Anti- cancer. Crizotinib. Dasatinib. Erlotinib. Everolimus. Lapatinib. Nilotinib. Pazopanib. Sunitinib. Vandetanib. Venurafenib. Anti- infective. Erythromycin. Halofantrine. Maraviroc. Primaquine. Quinine. Rilpivirine. Anti- cholesterol. Atorvastatin. Lovastatin. Simvastatin. Cardiovascular. Amiodarone. Apixaban. Clopidogrel. Dronedarone. Eplerenone. Felodipine. Nifedipine. Quinidine. Rivaroxaban. Ticagrelor. Central nervous system Alfentanil (oral). Buspirone. Dextromethorphan. Fentanyl (oral). Ketamine (oral). Lurasidone. Oxycodone. Grapefruit juice shouldn't. Grapefruit drug interactions linked to 85 medications, says study Lisa Brenner Katz Caption. Photo by Stefan Van der Straeten via Flickr Creative Commons.
Pimozide. Quetiapine. Triazolam. Ziprasidone. Gastrointestinal. Immunosuppressants. Cyclosporine. Everolimus. Sirolimus. Tacrolimus. Urinary tract. Darifenacin. Fesoterodine. Solifenacin. Silodosin. Tamsulosin.
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